I agree, Grounding problems are always a hum as opposed to a noise, generally
I had a heap of ground loop issues when I first started setting up to make music, now I'm a real stickler for checking everything at every point to make sure I don't run into that problem again,
Try isolating things if you can, like if you can run the cv converter via usb power, run everything off your macs battery and see if the sound still persists, if it does, it aint a ground loop and you have bigger issues...
Also try plugging your whole setup into one powerboard and then plug that into different outlets throughout your house or a friends house to test. I once lived in a house that only had grounding issues in the room I chose to setup in.
But yeah. my guess is bad m-audio gear.
If it is a ground loop I'd actually hazard a guess it's your synths power supply, probably some badly wired 9v or 12v powerpack...
